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KMID : 0191119990140010057
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Journal of Korean Medical Science
1999 Volume.14 No. 1 p.57 ~ p.62
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Primary carcinoid tumor of the testis: immunohistochemical, ultrastructural and DNA flow cytometric study of two cases
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Kim HJ
Cho MY/Park YN/Kie JH
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Abstract
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Primary testicular carcinoid tumor, occupying 0.23% of testicular neoplasm, is a rare and indolent
neoplasm with the potential for distant metastasis. We present two cases of primary pure carcinoid
tumor of the testis. Both patients were 36 years old. Physical examination revealed testicular mass
with and without tenderness. The preoperative serum levels of beta-human chorionic gonadotropin and
alpha-fetoprotein were normal and neither patient had carcinoid syndrome. The tumors measured 7.5x6x4
cm and 5.5x5x4 cm in size. Histologically, immunohistochemically and ultrastructurally, the tumors
showed typical features of the carcinoid tumor. Case 1 showed extensive tumor necrosis and vascular
invasion. DNA flow cytometric analysis showed aneuploidy with DNA index of 1.47 and S+G2M of 14.0%
in case 1 and tetraploidy with DNA index of 1.96 and S+G2M of 22.1% in case 2. Both patients have been
well without any signs of metastasis after operation for 24 months in case 1 and for 16 months in case
2.
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